Memory consolidation in Drosophila operant visual learning.
Open Access
- 1 July 1997
- journal article
- Published by Cold Spring Harbor Laboratory in Learning & Memory
- Vol. 4 (2) , 205-218
- https://doi.org/10.1101/lm.4.2.205
Abstract
A new conditioning procedure, developed for the operant learning paradigm at the flight simulator, leads to stronger learning scores in wild-type flies. This procedure produces mean learning indices up to LI = 0.52. The heat-avoidance behavior acquired during training is very difficult to extinguish during extinction. Memory decays quickly during the first 3 hr after training and still is measurable 48 hr later. Disruption experiments demonstrate that memory can be disrupted by cold anesthesia within the first approximately 20 min after training, whereas KCl- and CXM-feeding regimens abolish memory soon after training and 3 hr later, respectively. These results initially suggest at least three distinct memory phases involved in memory consolidation in Drosophila after operant conditioning.Keywords
This publication has 60 references indexed in Scilit:
- Induction of a dominant negative CREB transgene specifically blocks long-term memory in DrosophilaCell, 1994
- DrosophilaMutations that Alter Ionic Conduction Disrupt Acquisition and Retention of a Conditioned Odor Avoidance ResponseJournal of Neurogenetics, 1986
- Reduction of two voltage-dependent K+ currents mediates retention of a learned associationBehavioral and Neural Biology, 1985
- Classical conditioning and retention in normal and mutantDrosophila melanogasterJournal of Comparative Physiology A, 1985
- Drosophila Learning: Behavior and biochemistryBehavior Genetics, 1984
- Learning in three species of diptera: The blow flyPhormia regina, the fruit flyDrosophila melanogaster, and the house flyMusca domesticaBehavior Genetics, 1984
- Conditioned courtship inDrosophila and its mediation by association of chemical cuesBehavior Genetics, 1983
- Potassium Currents in Drosophila : Different Components Affected by Mutations of Two GenesScience, 1983
- A Cellular Mechanism of Classical Conditioning in Aplysia : Activity-Dependent Amplification of Presynaptic FacilitationScience, 1983
- Associative Behavioral Modification in Hermissenda : Cellular CorrelatesScience, 1980