NANOPHTHALMOS - A PERSPECTIVE ON IDENTIFICATION AND THERAPY

  • 1 January 1982
    • journal article
    • research article
    • Vol. 89  (9) , 1006-1012
Abstract
Nanophthalmos is a rare and blinding disease. Diagnostic features include a small eye, small cornea shallow anterior chamber, narrow angle, high lens/eye volume ratio and uveal effusion. Intraocular surgery has a high rate of diastrous complications and blindness. The 32 eyes (16 patients) presented are in 3 categories based on angle closure and intraocular pressure levels. Treatment methods included medication, laser iridotomy and gonioplasty, peripheral iridectomy, filtration surgery and cataract extraction. Glaucoma medication was effective, although miotics sometimes increased pupillary block. Laser iridotomy was successful in 83% of 6 eyes; laser gonioplasty in 91.6% of 12 eyes. Peripheral iridectomy succeeded in 2 of 7 eyes, and filtering operations provided tension control in 2 of 5 eyes. Of 15 eyes undergoing filtration surgery 13 suffered severe postoperative visual loss. Cataract extraction improved vision in only 3 of 6 eyes. Apparently, surgery in nanophthalmic eyes had an extremely high complication rate with disastrous results. Medication and laser therapy are the procedures of choice for angle-closure glaucoma in nanophthalmos.

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