ON THE UPTAKE OF NYSTATIN BY SACCHAROMYCES-CEREVIAIAE .1. BASIC CONSIDERATIONS
- 1 January 1981
- journal article
- research article
- Vol. 30 (121-) , 139-151
Abstract
The uptake of nystatin by sensitive S. cerevisiae cells was studied as a function of temperature and nystatin concentration. Following analysis of the data, kinetic rate constants and a monolayer capacity are calculated. This shows that .apprx. 13 times more nystatin is taken up than can be supported by the cell surface. The process is accompanied by an activation energy of 41.6 kJ mol-1. These data apparently support a rapid uptake process onto the cell wall followed by a slower diffusion process through the wall to the membrane.This publication has 7 references indexed in Scilit:
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