Diabetes‐induced overexpression of endothelin‐1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP‐ribose) polymerase activation
Open Access
- 3 June 2003
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 17 (11) , 1-18
- https://doi.org/10.1096/fj.03-0013fje
Abstract
We hypothesize that poly (ADP‐ribosyl)ation, that is, poly (ADP‐ribose) polymerase (PARP)‐dependent transfer of ADP‐ribose moieties from NAD to nuclear proteins, plays a role in diabetic nephropathy....Keywords
Funding Information
- American Diabetes Association Research Foundation
- National Institutes of Health (DK59809-01, HL/DK 71215-01)
- Juvenile Diabetes Research Foundation International (4-200-421)
This publication has 60 references indexed in Scilit:
- Early oxidative stress in the diabetic kidney: effect of DL-α-lipoic acidFree Radical Biology & Medicine, 2003
- Hyperglycemia increases endothelial superoxide that impairs smooth muscle cell Na+-K+-ATPase activityAmerican Journal of Physiology-Cell Physiology, 2002
- How does glucose generate oxidative stress in peripheral nerve?Published by Elsevier ,2002
- Cellular mechanisms in the development and progression of diabetic nephropathy: Activation of the DAG-PKC-ERK pathwayAmerican Journal of Kidney Diseases, 2001
- High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells.Diabetes, 2000
- Aldose reductase inhibitors: therapeutic implications for diabetic complicationsExpert Opinion on Investigational Drugs, 1999
- Contributions of polyol pathway to oxidative stress in diabetic cataractThe FASEB Journal, 1999
- Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.Journal of Clinical Investigation, 1997
- Renal Cortical Expression of mRNAs for Antioxidant Enzymes in Normal and Diabetic RatsBiochemical and Biophysical Research Communications, 1997
- Effect of diabetes mellitus induced by streptozotocin on renal Superoxide dismutases in the ratVirchows Archiv B Cell Pathology Including Molecular Pathology, 1991