A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched
- 1 October 1989
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 341 (6242) , 508-513
- https://doi.org/10.1038/341508a0
Abstract
The patterning of cells in insect segments requires the exchange of information between cells, which in Drosophila depends on the activity of members of the segment-polarity class of genes. Here we report the molecular characterization of one such gene, patched. We find that patched encodes a large protein with several possible membrane-spanning domains and is expressed in a complex pattern during embryogenesis.Keywords
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