Rubella IgM Antibodies in Sera from Infants Born after Maternal Rubella Later than the 12th Week of Pregnancy

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Abstract
The outcome of 338 pregnancies complicated by serologically confirmed rubella after the 12th wk of gestation is reported. Therapeutic abortions were performed on 93 women, 1 pregnancy resulted in a spontaneous abortion and 5 resulted in stillbirths. Cord blood or a sample collected at an age of 0-2 mo. from 209 liveborn infants were tested for rubella Ig[immunoglobulin]M antibodies after sucrose density gradient ultracentrifugation. Such antibodies were detected in samples from approximately 33% of infants born after maternal rubella in the 4th and 5th mo. of gestation but only in 11% of infants born after maternal rubella later in pregnancy. The classical symptoms of congenital rubella were not observed, with the possible exception of a suspected unilateral hearing loss in 1 infant born after maternal rubella in the 5th mo. of pregnancy.