Metabolic Studies in a Case of Fibrocystic Disease of the Pancreas with Reference to Treatment and to the Incidence of Bone Disease

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Abstract
Detailed metabolic balance data in a case of fibrocystic disease of the pancreas are presented. The results confirmed that pancreatin decreased fecal N and, to a lesser extent, fat excretion; these results were independent of dietary intake or the presence of infection. 19 nor-testosterone phenyl propionate ("durabolin") decreased urine N excretion, both in the presence and absence of infection. The Ca balance data showed a high fecal Ca excretion, only very slightly improved by large doses of oral and intramuscular vitamin D; these results are considered to indicate a liability to deficiency of Ca but not of vitamin D, and this correlates with the frequency of osteoporosis and the rarity of rickets.