Abstract
In 1991 the Senate Committee on Appropriations approached the National Institute of Child Health and Human Development with a request and an offer. The request was to design a definitive study to determine the effects of illicit drugs on pregnancy. The offer was substantial financial support to conduct the study. The response caused some surprise.1 My colleagues and I recommended that funds not be allocated because problems in identifying drug use, legal obstacles, privacy issues, and confounding as a result of other factors in women who abuse drugs made a definitive study extremely difficult if not impossible to conduct.Our . . .