Suspected research fraud: difficulties of getting at the truth

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Abstract
Introduction In April 1992 the BMJ published a randomised controlled trial on the effects of dietary intervention to prevent further heart attacks in susceptible patients.1 One of its key findings was that a year of a low fat, fibre rich diet almost halved the risk of death from all causes. This study went on to become a “citation classic,” cited 225 times (at the time of writing), including in guidelines, and its lead author, Dr Ram B Singh, went on to publish many papers in other journals. During the process, he became the focus of a concerted, but informal, international investigation into suspicions of scientific misconduct and data fabrication, spanning well over a decade.

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