INACTIVATION OF CHORIONIC GONADOTROPHIN BY X-RAYS

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Abstract
Chorionic gonadotrophin has been found to be highly resistant to the action of radium [Zondek, 1935]. The experiments with X-rays presented below show that this is true only for concentrated solutions. It should be noted that enzymes [Dale, 1940] as well as simple chemicals such as acetylcholine [Dale, 1943], and even organized elements, such as arbacia spermatozoids [Evans, Slaughter, Little & Failla, 1942], virus [Friedewald & Anderson, 1940; Lacassagne & Nyka, 1938; Luria & Exner, 1941] and erythrocytes in certain limits [Halberstaedter & Goldhaber, 1943] show a similar behaviour, that is their response to X-irradiation decreases as their concentration in the medium is increased. The effect of X-rays depends also on the constitution of the medium: it has been shown that certain materials in the medium can protect the irradiated object from the action of X-rays. It seems probable that the further study of this phenomenon could lead to a

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