Glycolytic enzymes in human brain

Publisher Website
Google Scholar
Abstract
Six glycolytic enzymes of the anaerobic and aerobic routes of carbohydrate metabolism have been examined in human cerebral and cerebellar white and grey matter, dorsal and lumbar cord. A comparison of activities in these regions shows that enzymes of the Embden-Meyerhof pathway are more active in grey matter than in white matter. The very much lower absolute activities of the dehydrogenases of the direct oxidative pathways are relatively more active than other enzymes in white matter. Phosphorylase activity in all regions suggests that glycogen metabolism probably functions in the brain and the cord. Comparisons have been made with other mammalian brains where possible.