Isolated sphenoid sinusitis due toPseudallescheria boydii

Abstract
A case of sphenoid sinusitis due toPseudallescheria boydiiis described in a 52-year-old non-immunocompromised woman. Treatment should always involve surgical drainage, and antifungal chemotherapy may be of benefit if there is histological evidence of invasion of surrounding tissue. ForP. boydiiinfection miconazole should be the agent of choice, rather than amphotericin B. For this reason it is important to obtain culture and histological examination of sinus contents if fungal infection is suspected.

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