Guilty until proven innocent: the case of NPC1 and cholesterol
- 1 September 2005
- journal article
- Published by Elsevier in Trends in Biochemical Sciences
- Vol. 30 (9) , 498-505
- https://doi.org/10.1016/j.tibs.2005.07.007
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- NPC1 late endosomes contain elevated levels of non-esterified (‘free’) fatty acids and an abnormally glycosylated form of the NPC2 proteinBiochemical Journal, 2005
- Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C–related protein reveals a primordial role in subcellular sphingolipid distributionThe Journal of cell biology, 2004
- Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomesJournal of Lipid Research, 2003
- Modulation of Cellular Cholesterol Transport and Homeostasis by Rab11Molecular Biology of the Cell, 2002
- Sphingomyelin Modulates the Transbilayer Distribution of Galactosylceramide in Phospholipid MembranesJournal of Biological Chemistry, 2002
- Niemann-Pick Type C1 (NPC1) Overexpression Alters Cellular Cholesterol HomeostasisJournal of Biological Chemistry, 2000
- Topological Analysis of Niemann-Pick C1 Protein Reveals That the Membrane Orientation of the Putative Sterol-sensing Domain Is Identical to Those of 3-Hydroxy-3-methylglutaryl-CoA Reductase and Sterol Regulatory Element Binding Protein Cleavage-activating ProteinJournal of Biological Chemistry, 2000
- Vectorial Budding of Vesicles by Asymmetrical Enzymatic Formation of Ceramide in Giant LiposomesBiophysical Journal, 2000
- The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterolBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1994
- Type C Niemann-Pick disease: A murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in liverBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1992