The effect of androgen on canine prostatic secretion

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Abstract
The volume and acid phosphatase concentration of and the zinc–65 output in stimulated prostatic fluid were significantly increased by testosterone treatment of intact dogs. The alkaline phosphatase, glucose, fructose, total protein, sodium, potassium, chloride and citric acid concentration were not statistically significantly changed. The cholesterol concentration in the fluid was significantly decreased by androgen therapy. The finding that bilateral vasectomy caused a significant decrease of the alkaline phosphatase concentration of prostatic fluid of intact control dogs suggests that the vasa deferentia contribute alkaline phosphatase to canine prostatic fluid. The results furthermore indicate that the dog prostate not only secretes small quantities of fructose and glucose but also increases the concentration of fructose in stimulated prostatic fluid on testosterone treatment.

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