Excessive Uterine Bleeding: Antigonad Effect of Prolactin

Publisher Website
Google Scholar
Abstract
There is an important physiological relationship between the lactogenic factor of the ant. pituitary and the functions of the ovary and endometrium. The lactogenic hormone is antigonadal in its effects. The use of the lactogenic hormone (prolactin), in a recent series of 34 cases of functional menorrhagiametrorrhagia has controlled the bleeding successfully in every case. Equine gonado-trophin was used following prolactin for 22 of 34 patients in order to improve their ovarian function. Only 5 (23%) patients with uterine fibromyomata required surgery. The other 17 (77%), who had fibroid conditions, improved satisfactorily with prolactin treatment only. Evidence is presented that prolactin has a transitory, harmless effect physiologically, and that there may be other factors partially responsible for excessive uterine bleeding than those which are now recognized. This method of controlling excessive uterine bleeding was studied for a period of 4.5 yrs.

This publication has 3 references indexed in Scilit: