Studies of Sodium Fluoride Effects (a) On Human Otosclerotic Bone (b) On Prevention of Experimental Osteoporosis in Rats (c) Synergistic Action with Phosphates
- 1 January 1968
- journal article
- research article
- Published by Taylor & Francis in Acta Oto-Laryngologica
- Vol. 65 (1-6) , 120-130
- https://doi.org/10.3109/00016486809120950
Abstract
In newborn rats, NaF in optimal doses promotes bone calcification both by decreasing bone resorption and stimulating calcium deposition. Sodium fluoride also has a preventive action on heparine-induced, cortisone-induced and fracture-induced osteoporosis in 6- to 8-week-old rats, especially if given both before and after experimental fracture and combined after fracture with Na2HPO4 and KH2PO2. Both the above results were observed by the semi-quantitative evaluation of tetracycline labeling vs. microchemical calcium assays.Keywords
This publication has 7 references indexed in Scilit:
- EFFECT OF PHOSPHATE SUPPLEMENTS IN PATIENTS WITH FRACTURESThe Lancet, 1967
- Heparin OsteoporosisJAMA, 1965
- Heparin Enhancement of Factors Stimulating Bone Resorption in Tissue CultureScience, 1965
- SOME EFFECTS OF ADMINISTERING SODIUM FLUORIDE TO PATIENTS WITH PAGET'S DISEASEThe Lancet, 1962
- Growth of embryonic avian and mammalian tibiae on a relatively simple chemically defined mediumExperimental Cell Research, 1961
- Effect of Sodium Fluoride on Calcium Metabolism of Human BeingsNature, 1961
- The response of the oral mucosa and periodontium to simultaneous administration of cortisone and somatotropic hormone in young adult male ratsArchives of Oral Biology, 1960