Cytogenetic Findings in Moderate and Severe Mental Retardation A Study of an Institutionalized Population of 1991 Patients
- 1 June 1984
- journal article
- Published by Wiley in Acta Paediatrica
- Vol. 73 (s313) , 3-23
- https://doi.org/10.1111/j.1651-2227.1984.tb10001.x
Abstract
The cytogenetic data of a large scale study in an institutionalized population of 1991 moderately and severely mentally retarded patients are presented. In 21.3% of these patients a chromosomal aberration was diagnosed (14.9% Down syndrome patients and 3.5%“other chromosomal anomalies”). A fragile X screening was performed in 354 males, and was found to be positive in 57 (16.1% positive). Different chromosomal variants were present in another 6% of this population. Detailed results are presented on the different groups of chromosomal aberrations.Keywords
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