The flow cytometry of melanocytic skin lesions
Open Access
- 1 November 1988
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 58 (5) , 606-609
- https://doi.org/10.1038/bjc.1988.268
Abstract
DNA flow cytometry was performed on formalin fixed, paraffin embedded melanocytic naevi DNA aneurploidy was detected in all three types of naevus but was significantly more frequent in those naevi accepted as precursors of malignancy that is, dysplastic and congenital hairy naevi. It may be that the presence of DNA aneuploidy has prognostic significance in these naevi. Technical problems were encountered in the analysis of data from melanocytic lesions so that caution is recommended in interpretation of studies using formalin fixed tissue.Keywords
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