Inhalation Anesthetics and Permeability of Human Erythrocytes to Monosaccharides

Open Access
Publisher Website
Google Scholar
Abstract
Studies of the effects of inhalation anesthetics on membrane carrier systems were carried out using, as a prototype, entry of monosaccharides into human erythrocytes. The data obtained lead to the proposal that, by acting as penetrating competitive inhibitors in a system which involves uphill counter-transport mechanisms, anesthetics can result in either acceleration or inhibition of the rate of transport of monosaccharides across cell membranes, depending upon the relative concentration of the anesthetic.