Reduction of Nosocomial Infection during Pediatric Intensive Care by Protective Isolation

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Abstract
To determine whether simple protective isolation reduces the incidence of nosocomial bacterial and fungal infection during pediatric intensive care, we randomly assigned 70 children who were not immunosuppressed and who required mechanical ventilator support and three or more days of intensive care to receive standard care (n = 38) or protective isolation (n = 32) with the use of disposable, nonwoven, polypropylene gowns and nonsterile latex gloves. Risk factors predisposing patients to infection were comparable in the two groups.