Course of localized adenocarcinoma of the prostate treated by radical prostatectomy
- 1 January 1983
- journal article
- research article
- Published by Wiley in The Prostate
- Vol. 4 (5) , 461-472
- https://doi.org/10.1002/pros.2990040505
Abstract
Among 562 patients with histologic stage B‐1, B‐2, or C adenocarcinoma of the prostate treated by radical prostatectomy and pelvic lymphadenectomy, analysis revealed that increasing histologic stage, tumor size, degree of capsular invasion, seminal vesicle involvement, and histologic grade all were highly correlated with both local and systemic progression (log‐rank two‐sided P < 0.0001). No variable correlated with survival–a result that may reflect appropriate adjuvant therapy given at the time of progression. The death rate from prostatic cancer did appear to rise progressively with increase of stage. Overall, the projected 10‐year survival was 76%.Keywords
This publication has 9 references indexed in Scilit:
- Presalvage prostate‐specific antigen (PSA) and PSA doubling time as predictors of biochemical failure of salvage cryotherapy in patients with locally recurrent prostate cancer after radiotherapyCancer, 2006
- Radical Perineal Prostatectomy for Clinical Stage B2 Carcinoma of the ProstateJournal of Urology, 1982
- The Present Status of Radical Prostatectomy for Stages A and B Prostatic CancerUrologic Clinics of North America, 1975
- Carcinoma of the Prostate: Biopsy and Conservative TherapyJournal of Urology, 1972
- Regression Models and Life-TablesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1972
- Pathologic Differentiation and Prognosis of Prostatic CarcinomaJAMA, 1969
- A generalized Wilcoxon test for comparing arbitrarily singly-censored samplesBiometrika, 1965
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958