Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3′-azido-2′,3′-dideoxythymidine
Open Access
- 1 May 1997
- journal article
- Published by Elsevier in Mutation Research - Genetic Toxicology and Environmental Mutagenesis
- Vol. 390 (3) , 223-231
- https://doi.org/10.1016/s1383-5718(97)00014-4
Abstract
No abstract availableKeywords
This publication has 24 references indexed in Scilit:
- Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesisAntimicrobial Agents and Chemotherapy, 1994
- Effect of anti-HIV 2′-β-fluoro-2′,3′-dideoxynucleoside analogs on the cellular content of mitochondrial DNA and on lactate productionBiochemical Pharmacology, 1994
- Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosidesAntimicrobial Agents and Chemotherapy, 1994
- Preferential incorporation of 3′‐azido‐2′,3′‐dideoxythymidine into telomeric DNA and Z‐DNA—containing regions of chinese hamster ovary cellsMolecular Carcinogenesis, 1993
- Thymidine and zidovudine metabolism in chronically zidovudine-exposed cells in vitroBiochemical Pharmacology, 1991
- The pc12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogsBiochemical Pharmacology, 1991
- Mitochondrial Myopathy Caused by Long-Term Zidovudine TherapyNew England Journal of Medicine, 1990
- Incorporation of 3’-Azido-3’-deoxythymidine into Cellular DNA and Its Removal in a Human Leukemic Cell LineCancer Communications, 1990
- Biochemical pharmacology of zidovudine in human T-lymphoblastoid cells (CEM)AIDS, 1989
- Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.Proceedings of the National Academy of Sciences, 1986