Vasectomy and health. Results from a large cohort study

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Abstract
In this cohort study 10,590 vasectomized men from 4 cities, along with a paired neighborhood control for each, were interviewed. The times between procedure data and interview or death ranged from < 1-41 yr, with median equal to 7.9 yr and with 2318 pairs having 10 yr of follow-up. Participant reports of diseases or conditions that might possibly be related to vasectomy through an immunopathological mechanism were validated by direct contact with physicians and review of medical records. The suggestions of immunopathological consequences of vasectomy within the period of follow-up were not supported. Except for epididymitis-orchitis, the incidence of diseases for vasectomized men was similar or lower than for their paired controls.