Tissue perfusion in humans studied by fourier velocity distribution, line scan, and echo‐planar imaging

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Abstract
In tissue perfusion studies, FT velocity distribution imaging (VDI) intrinsically distinguishes signals from moving blood and volume-averaged tissue. Results in human thyroid gland, in vivo, using VDI line scan technique demonstrated separation of moving blood signal from glandular tissue. while VDI inner-volume echo-planar imaging of brain showed only CSF velocity above the image noise level. New alternating polarity gradient sequences which permit separation of diffusion and slow velocity are discussed. A novel method of 3D FT imaging (two spatial and one velocity dimension) combining inner-volume imaging and echo-planar imaging with velocity resolution of 0.15 mm / s per pixel is demonstrated. A novel graphical method of calculation and display of diffusion dependence in pulsed gradient sequences is presented. © 1990 Academic Press, Inc.