False-Positive Rose-Waaler Rheumatoid Factor Titre Given by Anti-Ruminant IgM Antibody
- 30 November 1976
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 31 (6) , 451-455
- https://doi.org/10.1111/j.1423-0410.1976.tb04461.x
Abstract
An antibody against ruminant (goat, sheep, bovine) IgM [immunoglobulin M] is described which also cross-reacts with rabbit IgM. The antibody was found in the serum of a patient with adult celiac disease and a selective IgA deficiency. This patient gave a false high Rose-Waaler rheumatoid factor titer due to the presence of the serum antibody to rabbit IgM that was capable of agglutinating rabbit antibody-sensitized erythrocytes.Keywords
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