A Test for Spinal-Fluid Alcohol in Torula Meningitis

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Abstract
CASES of chronic meningitis in which an organism cannot be recovered from the spinal fluid are occasionally encountered and pose a difficult clinical problem. When the disease is accompanied by a persistently low spinal-fluid sugar, the differential diagnosis commonly becomes narrowed to carcinomatous meningitis, sarcoidosis of the meninges and cryptococcosis or other fungal meningitis. Any laboratory aids are of benefit in this situation, and for this reason we are reporting a test that, when positive, should strongly suggest the diagnosis of fungal meningitis.Yeasts uniformly contain the enzyme alcohol dehydrogenase whereas bacteria do not, and therefore the end product of . . .

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