AN UNUSUAL CASE OF PRECOCIOUS PUBERTY ASSOCIATED WITH OVARIAN DYSGERMINOMA

Publisher Website
Google Scholar
Abstract
ADESCRIPTION is given of the only case of precocious puberty associated with dysgerminoma in which hormonal assays have been carried out. The author is indebted to Professor Macafee and Professor Allen, both of Belfast, for permission to describe it. The patient, aged 8 years, was admitted to hospital on June 22, 1948, with a history of swelling of the breasts and growth of axillary and pubic hair for two years. She had the general appearance of a girl of 12 (Fig. 1), though ossification (wrists) showed an age of about 7 or 8; breast development was equal to that of a girl of 16 or 17. There were no signs of virilism other than some facial acne. There had been intermittent vaginal bleeding for the past six months, and simultaneously the abdomen had slightly increased in size; during the week prior to admission to hospital this increase had been very marked. A paracentesis was immediately performed and 11 pints of straw-colored fluid were drawn off, after which it was possible to palpate a large, hard tumor which appeared to arise from the pelvis.

This publication has 2 references indexed in Scilit: