DECREASED IONIZED CALCIUM DURING THERAPEUTIC PLASMA-EXCHANGE PHERESIS AND PLATELET PHERESIS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 146  (6) , 260-263
Abstract
Marked reductions in ionized Ca were observed in normal donors undergoing platelet pheresis using acid-citrate dextrose formula A (ACD-A) anticoagulant, and in patients undergoing therapeutic plasma exchange pheresis using citrate phosphate dextrose (CPD)-ABO compatible plasma. Donors showed a greater tendency to symptoms of hypocalcemia, although patients receiving CPD plasma demonstrated lower values of ionized calcium. There may be important differences in the availability of Ca from plasmas containing these 2 anticoagulants.