Use of NPE-Protecting Groups for the Preparation of Oligonucleotides Without Using Nucleophiles During the Final Deprotection

This publication has 22 references indexed in Scilit:

• The p-nitrophenylethyl (NPE) group: A versatile new blocking group for phosphate and aglycone protection in nucleosides and nucleotides
  Published by Elsevier ,2001
• Synthesis and physicochemical studies of partially phosphate-methylated oligodeoxyribonucleotides
  Tetrahedron Letters, 1993
• The Functionalization of Oligonucleotides Via Phosphoramidite Derivatives
  Tetrahedron, 1993
• The 2-(acetoxymethyl)benzoyl (AMB) group as a new base-protecting group, designed for the protection of (phosphate) modified oligonucleotides.
  Tetrahedron Letters, 1990
• The allylic protection method in solid-phase oligonucleotide synthesis. An efficient preparation of solid-anchored DNA oligomers
  Journal of the American Chemical Society, 1990
• A new protected acyl protecting group for exocyclic amino functions of nucleobases
  Tetrahedron Letters, 1990
• Fast oligonucleotide deprotection phosphoramidite chemistry for DNA synthesis
  Tetrahedron Letters, 1990
• Synthesis of phosphate-methylated DNA fragments using 9-fluorenylmethoxycarbonyl as transient base protecting group
  The Journal of Organic Chemistry, 1989
• The isopropoxyacetic group for convenient base protection during solid-support synthesis of oligodeoxyribonucleotides and their triester analogs
  Nucleic Acids Research, 1988
• The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups
  Nucleic Acids Research, 1987