Plasmid-Mediated Resistance to Gentamicin in Staphylococcus aureus
Open Access
- 1 October 1977
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 12 (4) , 513-517
- https://doi.org/10.1128/aac.12.4.513
Abstract
Two strains isolated from a recent outbreak of infections by gentamicin-resistant Staphylococcus aureus were examined to determine whether genetic control of this resistance is plasmid or chromosomally mediated. Curing techniques indicated a plasmid location in both strains. Physical isolation and characterization of the plasmid deoxyribonucleic acid from one strain revealed that the determinant for gentamicin resistance resides on a 50S plasmid.Keywords
This publication has 15 references indexed in Scilit:
- Variation in the Susceptibility of Strains of Staphylococcus aureus to Oxacillin, Cephalothin, and GentamicinAntimicrobial Agents and Chemotherapy, 1976
- Gentamicin resistance in methicillin-sensitive and resistant Staphyococcus aureusJournal of Antimicrobial Chemotherapy, 1976
- GENTAMICIN-RESISTANT STAPHYLOCOCCIThe Lancet, 1976
- EPIDEMIC INFECTION BY A GENTAMICIN-RESISTANT STAPHYLOCOCCUS AUREUS IN THREE HOSPITALSThe Lancet, 1976
- GENTAMICIN RESISTANCE IN STAPHYLOCOCCUS AUREUSThe Lancet, 1976
- Susceptibility of clinical isolates of Staphylococcus aureus to killing by oxacillinCanadian Journal of Microbiology, 1975
- Evidence for Participation of Autolysins in Bactericidal Action of Oxacillin on Staphylococcus aureusAntimicrobial Agents and Chemotherapy, 1974
- Enhancement of the Effects of Anti-Staphylococcal Antibiotics by AminoglycosidesAntimicrobial Agents and Chemotherapy, 1974
- The Increased Rate of Loss of Penicillinase Plasmids from Staphylococcus aureus in the Presence of RifampicinJournal of General Microbiology, 1970
- Loss of Antibiotic Resistance in Staphylococcus Aureus Resulting from Growth at High TemperatureJournal of General Microbiology, 1966