A Comparison of Repeated High Doses and Repeated Standard Doses of Epinephrine for Cardiac Arrest Outside the Hospital
Open Access
- 26 November 1998
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 339 (22) , 1595-1601
- https://doi.org/10.1056/nejm199811263392204
Abstract
Clinical trials have not shown a benefit of high doses of epinephrine in the management of cardiac arrest. We conducted a prospective, multicenter, randomized study comparing repeated high doses of epinephrine with repeated standard doses in cases of out-of-hospital cardiac arrest.Keywords
This publication has 31 references indexed in Scilit:
- The Universal ALS Algorithm: An advisory statement by the Advanced Life Support Working Group of the International Liaison Committee On ResuscitationResuscitation, 1997
- Guidelines for advanced life supportResuscitation, 1992
- A Comparison of Standard-Dose and High-Dose Epinephrine in Cardiac Arrest outside the HospitalNew England Journal of Medicine, 1992
- High-Dose Epinephrine in Adult Cardiac ArrestNew England Journal of Medicine, 1992
- Comparison of different doses of epinephrine on myocardial perfusion and resuscitation success during cardiopulmonary resuscitation in a pig modelThe American Journal of Emergency Medicine, 1991
- Comparison of standard versus high-dose epinephrine in the resuscitation of cardiac arrest in dogsAnnals of Emergency Medicine, 1990
- The effect of epinephrine versus methoxamine on regional myocardial blood flow and defibrillation rates following a prolonged cardiorespiratory arrest in a swine modelThe American Journal of Emergency Medicine, 1987
- The effects of graded doses of epinephrine on regional myocardial blood flow during cardiopulmonary resuscitation in swine.Circulation, 1987
- Comparative effect of graded doses of epinephrine on regional brain blood flow during CPR in a swine modelAnnals of Emergency Medicine, 1986
- Dose-related response of centrally administered epinephrine on the change in aortic diastolic pressure during closed-chest massage in dogsAnnals of Emergency Medicine, 1985