A Histochemical Evaluation of Normal and Inflamed Human Gingivae

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Abstract
22 specimens of normal and inflamed human gingiva from 17 men and women ranging from 21 to 54 yrs. of age were examined using the Lillie and Hotchkiss leucofuchsin periodic acid methods for the study of ground substance, basement membrane and glycogen; the Gomori technic for the study of alkaline phosphatase; the hematoxylin and eosin technic, and control study for the presence of free aldehydes, free iodates and periodates, and preformed mineral deposits. Comparison of the normal and inflamed gingivae revealed reduction in connective tissue glycogen and ground substance, and thinning out of the basement membrane in chronic gingivitis. Alkaline phosphatase which was present in the endothelial cells of the scattered capillaries in the normal gingiva appeared concd. in the inflammatory cells, fibrocytes, endothelial cells, and collagen fibers in the areas of gingival inflammation. In zones of chronic inflammation hyperplastic epithelium presented an increased intracellular accumulation of glycogen.
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