The effect of lipophilic amines on the growth of hepatitis A virus in Frp/3 cells
- 1 September 1987
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 96 (3-4) , 289-296
- https://doi.org/10.1007/bf01320970
Abstract
Summary The effect of lipophilic amines on hepatitis A virus infection in a monkey cell line (Frp/3 cells) was studied. Ammonium chloride, amantadine, methylamine and dansylcadaverine inhibited viral antigen synthesis when added to the cells at least one hour after the attachment step. Results obtained suggest that the HAV entry pathway in Frp/3 cells follows an endocytic route and that viral uncoating takes probably place in endosomes and/or lysosomes.Keywords
This publication has 28 references indexed in Scilit:
- Entry of Poliovirus Type 1 and Mouse Elberfeld (ME) Virus into HEp-2 Cells: Receptor-mediated Endocytosis and Endosomal or Lysosomal UncoatingJournal of General Virology, 1985
- Propagation and assay of hepatitis A virus in vitroJournal of Virological Methods, 1984
- Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH.The Journal of cell biology, 1984
- Mechanism of Rabies Virus Entry into CER CellsJournal of General Virology, 1984
- Penetration of semliki forest virus from acidic prelysosomal vacuolesCell, 1983
- Pathway of vesicular stomatitis virus entry leading to infectionJournal of Molecular Biology, 1982
- Infectious entry pathway of influenza virus in a canine kidney cell line.The Journal of cell biology, 1981
- Adsorptive endocytosis of Semliki Forest virusJournal of Molecular Biology, 1980
- In vitro translation of mengovirus RNA deprived of the terminally‐linked (capping?) proteinFEBS Letters, 1978
- The Influence of DEAE-dextran on Plain and Synergistic Plaque Formation by Two PoxvirusesJournal of General Virology, 1969