More on Troponin Assays and Heparin

Abstract
A recent article [Troponin T and I Assays Show Decreased Concentrations in Heparin Plasma Compared with Serum: Lower Recoveries in Early than in Late Phases of Myocardial Injury (Clin Chem 2000;46:817–21)] concluded that “Until such methods [which are resistant to interference by both heparin and EDTA] are available, the sample of choice for cardiac troponin determinations is serum collected in tubes with or without gel, or in thrombin tubes with and without gel”. We believe that the conclusion is not supported by the data presented in the article.

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