Roferon-A in Combination with Tigason in Cutaneous T-Cell Lymphomas
- 1 January 1993
- journal article
- review article
- Published by S. Karger AG in Acta Haematologica
- Vol. 89 (1) , 28-32
- https://doi.org/10.1159/000204582
Abstract
In cutaneous T-cell lymphomas (CTCL; mycosis fungoides and Sézary syndrome), the standard therapies tend to be effective but not curative. Single drug therapy with either interferon-alpha or retinoids shows a response rate of about 45%. In this article, we report the results obtained in the treatment of CTCL with a combined therapy. To date, four clinical studies have been carried out using a combination of low doses of interferon-alpha and retinoids for treatment in the early stages of CTCL. The mechanism of action of this combination therapy is unknown.Keywords
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