THE EFFECT OF LOCAL CHANGES IN TEMPERATURE ON GAS TENSIONS IN THE TISSUES

Abstract
Air was injected subcutaneously by a method similar to that of Campbell but utilizing smaller volumes. The temp. of the surface was modified by immersion of the area in a H2O bath. The CO2 and O tensions were found to be profoundly modified by temp. changes. At ordinary temp. levels the CO2 tension was slightly below the alveolar air tension, and if the surface temp. was lowered to 10[degree] C it might be reduced to about 1/2 the alveolar tension. O tension varied between 88 and 14 mm., the highest values being observed with surface temp. of 42[degree] C. and the lowest with surface temp. of 22[degree] C. or lower. There was some tendency towards a minimum O tension at about 22[degree] C. Some measurements of the actual temp. in the subcutaneous tissues were made, as well as some determinations of the rate at which thermal and gaseous equilibria were attained. The effect of temp. on O tension is considered of importance in relation to anaerobic infections.

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