A new direct method for the synthesis of enantiomerically pure protected α-amino acids
- 1 January 1989
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 10,p. 644-645
- https://doi.org/10.1039/c39890000644
Abstract
The organozinc reagent (2), prepared from the protected β-iodo alanine derivative (3) using ultrasonic activation, is efficiently acylated using acid chlorides in the presence of (Ph3P)2PdCl2 to give high yields of enantiomerically pure protected γ-keto α-amino acids (4).Keywords
This publication has 0 references indexed in Scilit: