Chemical Synthesis and Disproportionation of N-Hydroxytyrosine.

Abstract
N-hydroxytyrosine was tested as a possible intermediate in the biosynthesis of the cyanogenic glucoside dhurrin. NMR and gas chromatography were used to identify reaction products. p-Hydroxyphenylpyruvic acid oxime is not an intermediate in the disproportionation of N-hydroxytyrosine and the earlier postulated involvement of .alpha.-ketoacid oximes in the disproportionation of N-hydroxyamino acids when refluxed under N based solely on CO2 production appears questionable.

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