Activity Rhythm in Peromyscus : Its Influence on Rates of Recovery from Nembutal
- 27 December 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 142 (3600) , 1682-1683
- https://doi.org/10.1126/science.142.3600.1682
Abstract
Injection of sublethal doses of Nembutal (sodium pentobarbital) into deer mice, Peromyscus maniculatus rufinus (Merriam), at diflerent times in their daily activity cycle revealed large differences in rates of recovery. By taking the phase of the circadian rhythm into account, the accuracy obtained in pharmaceutical and physiological bioassays could be increased.Keywords
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