The Preparation of Deoxyguanosine Oligomers on an Insoluble Polymer Support
- 1 June 1971
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 44 (6) , 1673-1677
- https://doi.org/10.1246/bcsj.44.1673
Abstract
The syntheses of deoxyguanosine-containing oligonucleotides, deoxyguanylyldeoxyguanylyldeoxyguanosine (d-GpGpG), deoxyguanylyldeoxyguanylyldeoxyguanylyldeoxyguanosine (d-GpGpGpG) and deoxyguanylyldeoxyguanylyldeoxyguanylylthymidine (d-GpGpGpT) have been described. Those nucleotidic materials were synthetized on an insoluble polymer support; the polymer was a copolymer of styrene, p-vinylbenzoic acid, and divinylbenzene. The blocking group used at the N-position of deoxyguanosine was di-p-methoxytrityl.Keywords
This publication has 15 references indexed in Scilit:
- Failure sequences in the solid phase synthesis of polypeptidesJournal of the American Chemical Society, 1970
- Oligonucleotide syntheses on insoluble polymer supports. II. Pentathymidine tetraphosphateThe Journal of Organic Chemistry, 1969
- Polynucleotides. LXXII. Deoxyribooligonucleotide synthesis on a polymer supportJournal of the American Chemical Society, 1967
- Stepwise Synthesis of Oligodeoxyribonucleotides on an Insoluble Polymer Support1,2Journal of the American Chemical Society, 1966
- Oligonucleotid‐Synthese an einem löslichen Polymeren als TrägerAngewandte Chemie, 1966
- Reactions on Polymer SupportsJournal of the American Chemical Society, 1964
- Studies on Polynucleotides. XXIV.1 The Stepwise Synthesis of Specific Deoxyribopolynucleotides (4).2 Protected Derivatives of Deoxyribonucleosides and New Syntheses of Deoxyribonucleoside-3″ Phosphates3Journal of the American Chemical Society, 1963
- Solid Phase Peptide Synthesis. I. The Synthesis of a TetrapeptideJournal of the American Chemical Society, 1963
- 2-Cyanoethyl Phosphate and its Use in the Synthesis of Phosphate Esters1Journal of the American Chemical Society, 1961
- Mercaptan Catalysis in Thermoneutral Free Radical ExchangeJournal of the American Chemical Society, 1957