Evaluation of a Commercial Latex Particle Agglutination Test for Rapid Diagnosis of Haemophilus influenzae Type b Infection

Publisher Website
Google Scholar
Abstract
The effectiveness of a commercially available latex particle agglutination test (Bactogen) in the diagnosis of invasive H. influenzae type b infection was evaluated. Bactogen correctly diagnosed all 27 patients with bacteriologically proven H. influenzae type b infection (sensitivity 100%). Two of 39 patients with proven, non-H. influenzae type b infections had false-positive tests (specificity 95%). One of 103 sera and 0 of 55 urine specimens from hospitalized adults contained detectable H. influenzae type b antigen. Bactogen is a sensitive, specific, commercially available test for rapid diagnosis of H. influenzae type b infection.