Effect of corticosterone on protein degradation in isolated rat soleus and extensor digitorum longus muscles
Open Access
- 1 March 1996
- journal article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 148 (3) , 501-507
- https://doi.org/10.1677/joe.0.1480501
Abstract
The net catabolic effect of glucocorticoids on protein metabolism is well documented but the acute and chronic effect of glucocorticoids on protein breakdown remains controversial. In the present studies protein breakdown was measured by the release of tyrosine from the isolated soleus and extensor digitorum longus (EDL) muscles of control rats and rats treated with corticosterone (10 mg/100 g body weight/day) for 5 days. The effect of corticosterone in arresting growth was confirmed since corticosterone-treated rats weighed significantly less than control rats after 2, 3, 4 and 5 days of treatment (PPPPPPPPPPPPJournal of Endocrinology (1996) 148, 501–507Keywords
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