Influence of Sulfanilamide and Related Compounds Upon Oxidation-Reduction Potentials of the Hemolytic Streptococcus.

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Abstract
Summary The addition of sulfanilamide to sterile broth or to cultures of the hemolytic streptococcus is accompanied by an elevation of the oxidation-reduction potential. This rise can be eliminated when the cocci are grown anaërobically or in cysteine broth. The addition of serum will slightly diminish this effect. Compounds related to sulfanilamide but lacking in bacteriostatic action are without effect upon the culture potentials. The relation of these potential effects to the action of the drug in streptococcal infections is discussed.

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