Prevalence of Shigella Enterotoxin 1 among Shigella Clinical Isolates of Diverse Serotypes

Publisher Website
Google Scholar
Abstract
Shigella enterotoxin 1 (ShET1) is a novel, iron-dependent, toxin encoded by chromosomal genes (setl). To determine the prevalence of this enterotoxin, 172 Shigella clinical isolates (and 10 enteroinvasive Escherichia coli [EIEC]) from distant areas worldwide, representing all 4 groups and 45 serotypes of Shigella, were screened for setl by DNA colony hybridization and polymerase chain reaction amplification. setl was present in all 22 Shigella fiexneri 2a strains tested but was rare in isolates of other Shigella serotypes (3.3%, 5/150) and not found in EIEC (0110). That ShET1 is found almost exclusively in S. flexneri 2a may help explain the epidemiologic predominance of this serotype in the developing world.

This publication has 0 references indexed in Scilit: