Audiometry as a possible indicator of quinine plasma concentration during treatment of malaria
- 1 November 1990
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 84 (6) , 765-767
- https://doi.org/10.1016/0035-9203(90)90069-q
Abstract
The spread of chloroquine-resistant malaria has led to a resurgence of quinine in clinical use. One of the well-known side effects of quinine, reversible hearing loss, is closely related to the plasma concentration. We suggest that this hearing effect could be used as an aid in therapy control when quinine drug assay is not available.Keywords
This publication has 4 references indexed in Scilit:
- Quinine causes isolated outer hair cells to change lengthNeuroscience Letters, 1990
- High-performance liquid chromatographic determination of quinine in plasma, whole blood and samples dried on filter paperJournal of Chromatography B: Biomedical Sciences and Applications, 1990
- Reversible hearing impairment related to quinine blood concentrations in guinea pigsLife Sciences, 1989
- Drug treatment and prevention of malariaEuropean Journal of Clinical Pharmacology, 1988