Small Molecule Inhibition of HDM2 Leads to p53-Mediated Cell Death in Retinoblastoma Cells
Open Access
- 1 September 2006
- journal article
- laboratory sciences
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 124 (9) , 1269-1275
- https://doi.org/10.1001/archopht.124.9.1269
Abstract
PurposeTo determine the efficacy of inducing p53-mediated cell death in retinoblastoma cells by Nutlin 3A, a small molecule HDM2 inhibitor.MethodsRetinoblastomaKeywords
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