Convenient and Short Route to a Key Intermediate in the Synthesis of Forskolin
- 1 June 1991
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 21 (12) , 1361-1367
- https://doi.org/10.1080/00397919108021283
Abstract
The intermediate 2, previously used in several synthetic sequences toward forskolin (1), has been synthesized from enone 3. The key step in the sequence is the 1,3-oxidative rearrangement of the tertiary alcohol 5, which allowed the easy introduction of the keto group at C-6 of 2.Keywords
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