Fluorescein Angiographic Behaviour of Iris Masses

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Abstract
Twenty-eight cysts and tumors involving the human iris were studied by fluorescein angiography of the anterior segment. Iris cysts usually showed abnormally dilated and tortuous feeding vessels, but only exceptionally did they leak fluorescein. Inflammatory masses presented massive dye leakage from tumor-involved and distant iris vessels. Benign stromal masses showed normal angiograms or dye leakage limited to the tumor site. Benign pigmented lesions were always angiographically silent, whereas malignant melanomas showed moderate to heavy leakage from the tumor. This leakage occasionally extended to uninvolved iris areas, especially the pupillary margin. A malignant melanoma of the iris was sometimes angiographically silent. Iris angiography is a useful, but not error free, method for the evaluation of iris masses.

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