Two DNA‐binding domains of Mga are required for virulence gene activation in the group A streptococcus
Open Access
- 1 March 2002
- journal article
- research article
- Published by Wiley in Molecular Microbiology
- Vol. 43 (6) , 1591-1601
- https://doi.org/10.1046/j.1365-2958.2002.02849.x
Abstract
Mga is a DNA‐binding protein that activates expression of several important virulence genes in the group A streptococcus (GAS), including those encoding M protein (emm), C5a peptidase (scpA) and Mg...Keywords
This publication has 60 references indexed in Scilit:
- SclA, a Novel Collagen-Like Surface Protein ofStreptococcus pyogenesInfection and Immunity, 2000
- The RofA Binding Site inStreptococcus pyogenesIs Utilized in Multiple Transcriptional PathwaysJournal of Bacteriology, 2000
- M-Like Proteins ofStreptococcus dysgalactiaeInfection and Immunity, 2000
- The Flesh‐Eating Bacterium: What's Next?The Journal of Infectious Diseases, 1999
- Molecular analysis of the role of the group A streptococcal cysteine protease, hyaluronic acid capsule, and M protein in a murine model of human invasive soft-tissue infection.Journal of Clinical Investigation, 1998
- Complementation of divergent mga genes in group A StreptococcusGene, 1996
- M‐related protein (Mrp) contributes to group A streptococcal resistance to phagocytosis by human granulocytesMolecular Microbiology, 1996
- Insertional inactivation ofvirRinStreptococcus pyogenesM49 demonstrates that VirR functions as a positive regulator of ScpA, FcRA, OF, and M proteinFEMS Microbiology Letters, 1995
- The identification of rofA, a positive‐acting regulatory component of prtF expression: use of an mγδ‐based shuttle mutagenesis strategy in Streptococcus pyogenesMolecular Microbiology, 1994
- PROTEIN-DNA RECOGNITIONAnnual Review of Biochemistry, 1984