Production ofl-Glutamic Acid fromdl-Hydantoin-5-propionic Acid by Microoganisms
- 1 January 1966
- journal article
- research article
- Published by Oxford University Press (OUP) in Agricultural and Biological Chemistry
- Vol. 30 (1) , 27-34
- https://doi.org/10.1080/00021369.1966.10858552
Abstract
Screening tests for obtaining microorganisms which can produce L-glutamic acid from hydantoin-5-propionic acid were carried out. Many strains of microorganism were found to possess this ability. It was newly found that the glutamic acid produced by these strains was exclusively L-form regardless of the stereochemical configuration of the substrate used. Among the selected strains Bacillus brevis ATCC 8185 showed the highest ability to produce L-glutamic acid. Some investigations for obtaining optimal conditions for producing L-glutamic acid using washed cells of Bacillus brevis ATCC 8185 were carried out. Under the adequate conditions using the reaction mixture containing 1.0% of DL-hydantoin-5-propionic acid, washed cells of this strain converted 90% of the DL-acid to L-glutamic acid. An assumptive pathway of producing L-glutamic acid from D-hydantoin-5-propionic acid was also discussed.This publication has 1 reference indexed in Scilit:
- The Bacterial Metabolism of l-Hydantoin-5-propionic Acid to Carbamylglutamic Acid and Glutamic AcidJournal of Biological Chemistry, 1963